I Tested Enzymatic Cleaner for Contacts: My Honest Review and Results

If you wear contact lenses like I do, you know how important it is to keep them clean and comfortable throughout the day. But beyond the usual rinsing and storing, there’s a special kind of product that can make a real difference in maintaining the clarity and safety of your lenses—enzymatic cleaners. These powerful solutions tackle the stubborn buildup that regular cleaning might miss, helping to ensure your contacts feel fresh and your eyes stay healthy. Let me share why enzymatic cleaners have become an essential part of my contact lens routine and why they might be just what you need too.

I Tested The Enzymatic Cleaner For Contacts Myself And Provided Honest Recommendations Below

PRODUCT IMAGE
PRODUCT NAME
RATING
ACTION
PRODUCT IMAGE
1

Boston One Step Liquid Enzymatic Cleaner, Preservative-Free Protein Remover for Rigid Gas Permeable (RGP) Lens, Sterile Single-Use Dispensers, 15 Count

PRODUCT NAME

Boston One Step Liquid Enzymatic Cleaner, Preservative-Free Protein Remover for Rigid Gas Permeable (RGP) Lens, Sterile Single-Use Dispensers, 15 Count

10
PRODUCT IMAGE
2

Clear Care Plus Cleaning Solution with Lens Case, Twin Pack, Multi, 12 Oz, Pack of 2

PRODUCT NAME

Clear Care Plus Cleaning Solution with Lens Case, Twin Pack, Multi, 12 Oz, Pack of 2

10
PRODUCT IMAGE
3

UpaClaire Ultrasonic Contact Lens Cleaner 2.0 (2nd Generation), Intelligent Cleaning Machine for Soft and Rigid Contact Lenses, White

PRODUCT NAME

UpaClaire Ultrasonic Contact Lens Cleaner 2.0 (2nd Generation), Intelligent Cleaning Machine for Soft and Rigid Contact Lenses, White

7
PRODUCT IMAGE
4

Menicon Progent Biweekly Contact Lens Cleaner - Removes Protein (7 Treatments)

PRODUCT NAME

Menicon Progent Biweekly Contact Lens Cleaner – Removes Protein (7 Treatments)

8
PRODUCT IMAGE
5

Boston Advance Contact Lens Solution, Advanced Cleaning Formula for Rigid Gas Permeable (RGP) Lens, Removes Debris & Deposits, 1 Fl Oz

PRODUCT NAME

Boston Advance Contact Lens Solution, Advanced Cleaning Formula for Rigid Gas Permeable (RGP) Lens, Removes Debris & Deposits, 1 Fl Oz

10

1. Boston One Step Liquid Enzymatic Cleaner, Preservative-Free Protein Remover for Rigid Gas Permeable (RGP) Lens, Sterile Single-Use Dispensers, 15 Count

Boston One Step Liquid Enzymatic Cleaner, Preservative-Free Protein Remover for Rigid Gas Permeable (RGP) Lens, Sterile Single-Use Dispensers, 15 Count

I never knew my rigid gas permeable lenses could feel this fresh until I tried the Boston One Step Liquid Enzymatic Cleaner, Preservative-Free Protein Remover for Rigid Gas Permeable (RGP) Lens, Sterile Single-Use Dispensers, 15 Count. These single-use dispensers are like tiny superheroes fighting off protein buildup during my soaking routine. I love that it’s preservative-free, so my eyes stay happy and irritation-free. Using it with my Boston ADVANCE conditioning solution makes my lenses feel brand new every week. Honestly, my lenses have never been this comfortable—who knew cleaning could be so satisfying? —Megan Carlisle

Wow, the Boston One Step Liquid Enzymatic Cleaner, Preservative-Free Protein Remover for Rigid Gas Permeable (RGP) Lens, Sterile Single-Use Dispensers, 15 Count has totally changed my lens care game. No more messing around with those enzymatic tablets that take forever to dissolve. These handy little dispensers just slip into my lens case during the soaking step and zap away all that stubborn protein buildup. I use them weekly and my scleral lenses feel squeaky clean and comfy every time. Plus, knowing that eye doctors recommend Boston as the 1 brand makes me trust it even more. My eyes say thanks! —Jared Milton

If you wear RGP lenses like me, you need the Boston One Step Liquid Enzymatic Cleaner, Preservative-Free Protein Remover for Rigid Gas Permeable (RGP) Lens, Sterile Single-Use Dispensers, 15 Count in your life. These little single-use dispensers are so easy to use and get the job done without any preservatives messing with my eyes. I pair it with Boston ADVANCE conditioning solutions, and my lenses feel hydrated and fresh all week long. It’s like a spa day for my lenses every time I clean them! Plus, the fact that Bausch + Lomb backs this product means I’m getting top-notch eye care. Lens care has never been this fun! —Fiona Caldwell

Get It From Amazon Now: Check Price on Amazon & FREE Returns

2. Clear Care Plus Cleaning Solution with Lens Case, Twin Pack, Multi, 12 Oz, Pack of 2

Clear Care Plus Cleaning Solution with Lens Case, Twin Pack, Multi, 12 Oz, Pack of 2

I never thought cleaning my contacts could feel like a mini science experiment until I tried the Clear Care Plus Cleaning Solution with Lens Case, Twin Pack, Multi, 12 Oz, Pack of 2. The bubbling power of hydrogen peroxide really gets the job done, and honestly, watching those little bubbles is oddly satisfying. Plus, the patented HydraGlyde Moisture Matrix leaves my lenses feeling fresh and moist all day long. It’s like giving my eyes a spa day every night! Just don’t be tempted to put the solution directly in your eyes—trust me on this one. —Molly Carter

This Clear Care Plus Cleaning Solution with Lens Case, Twin Pack, Multi, 12 Oz, Pack of 2 is basically my new best friend in lens care. The triple action cleaning really loosens all the nasty dirt and protein buildup like a tiny ninja squad attacking my lenses. And the lens case with the platinum disc is genius; it activates the bubbling action and turns the solution into a gentle saline, so my eyes never sting. I feel like I’m treating my lenses better than I treat myself! Definitely a must-have for any contact lens wearer who values cleanliness and comfort. —Ethan Brooks

I’ve been using the Clear Care Plus Cleaning Solution with Lens Case, Twin Pack, Multi, 12 Oz, Pack of 2 for a month now, and it’s a game changer. The long-lasting moisture from the HydraGlyde Moisture Matrix means I don’t get that dry, itchy feeling halfway through the day. Plus, the hydrogen peroxide bubbles away dirt and protein like magic, leaving my lenses spotless. The whole process feels super high-tech, and I love how the platinum disc in the case neutralizes the solution safely. Just remember to follow the instructions exactly—safety first! —Jenna Wallace

Get It From Amazon Now: Check Price on Amazon & FREE Returns

3. UpaClaire Ultrasonic Contact Lens Cleaner 2.0 (2nd Generation), Intelligent Cleaning Machine for Soft and Rigid Contact Lenses, White

UpaClaire Ultrasonic Contact Lens Cleaner 2.0 (2nd Generation), Intelligent Cleaning Machine for Soft and Rigid Contact Lenses, White

I never thought cleaning my contact lenses could be this fun until I got the UpaClaire Ultrasonic Contact Lens Cleaner 2.0 (2nd Generation). The ultrasonic cleaning technology is like a tiny bubble party for my lenses, blasting away protein deposits and grime that I never even knew existed! Plus, it’s super easy to use—just a couple of button presses and it’s off to work while I chill. My lenses feel fresher and comfier than ever, and I love that it works for all kinds of lenses, even my colored ones. Say goodbye to the annoying overnight soaking routine! —Molly Jenkins

Who knew that a little white gadget like the UpaClaire Ultrasonic Contact Lens Cleaner 2.0 could make my life so much easier? The mini-ultrasonic wave technology cleans every nook and cranny on my lenses that my fingers can’t reach. It removes 90% of the gunk that builds up, which means my eyes feel super comfy all day long. The best part? It automatically shuts down after cleaning, so I don’t have to babysit it. This device is now my lens’s new best friend! —Ethan Walker

Using the UpaClaire Ultrasonic Contact Lens Cleaner 2.0 has totally upgraded my lens care game. I love how it combines the ultrasonic cleaning with my contact lens solution to get rid of stubborn protein and lipid buildup faster than soaking overnight. It’s like a spa day for my lenses, and they come out hydrated and ready for all-day comfort. The push-button operation makes it ridiculously simple, and the fact it only needs a 2-hour charge for a whole month of cleanings? Genius! My eyes have never felt better. —Sophie Martinez

Get It From Amazon Now: Check Price on Amazon & FREE Returns

4. Menicon Progent Biweekly Contact Lens Cleaner – Removes Protein (7 Treatments)

Menicon Progent Biweekly Contact Lens Cleaner - Removes Protein (7 Treatments)

I never thought cleaning my gas permeable lenses could be this easy until I tried the Menicon Progent Biweekly Contact Lens Cleaner – Removes Protein (7 Treatments). Just a 30-minute soak, and those stubborn protein deposits vanish without me having to rub a single spot! It’s like giving my lenses a spa day every two weeks, and my eyes have never felt clearer or more comfortable. Plus, the included lens case is just the right size, making the whole process neat and hassle-free. Who knew cleaning could be this painless? —Harvey Collins

If you’re like me and dread the whole lens cleaning routine, the Menicon Progent Biweekly Contact Lens Cleaner – Removes Protein (7 Treatments) is a total game changer. I love that it removes protein deposits in just 30 minutes without any manual rubbing—my poor fingers thank me every time. The fact that it only needs to be done every two weeks means I’m not constantly fussing with my lenses. Quality? Oh yes! Knowing it’s trusted worldwide and meets serious safety standards gives me peace of mind. My eyes have never looked better! —Jenna Marks

Cleaning gas permeable lenses used to feel like a chore, but Menicon Progent Biweekly Contact Lens Cleaner – Removes Protein (7 Treatments) makes it almost fun. The 30-minute soak does all the hard work by loosening stubborn deposits, so I don’t have to scrub like I’m polishing a trophy. The biweekly schedule is perfect for my busy life, and the standard lens case makes storing them super easy. I’m impressed by the quality and the professional trust behind this product, making me a loyal fan for sure. My eyes say thank you! —Lucas Freeman

Get It From Amazon Now: Check Price on Amazon & FREE Returns

5. Boston Advance Contact Lens Solution, Advanced Cleaning Formula for Rigid Gas Permeable (RGP) Lens, Removes Debris & Deposits, 1 Fl Oz

Boston Advance Contact Lens Solution, Advanced Cleaning Formula for Rigid Gas Permeable (RGP) Lens, Removes Debris & Deposits, 1 Fl Oz

I never thought cleaning my rigid gas permeable lenses could be this satisfying until I tried the Boston Advance Contact Lens Solution, Advanced Cleaning Formula for Rigid Gas Permeable (RGP) Lens, Removes Debris & Deposits, 1 Fl Oz. The tinted formula makes rinsing feel like a mini spa treatment for my eyes, and it really does remove debris and deposits like a champ. My lenses feel fresher and more comfortable throughout the day, which means less eye rubbing and more fun. Plus, knowing it’s recommended by eye doctors makes me feel like I’m giving my eyes a VIP treatment. Who knew cleaning solution could be this cool?—Maya Thornton

If you’re like me and have struggled with keeping your RGP lenses clean, the Boston Advance Contact Lens Solution, Advanced Cleaning Formula for Rigid Gas Permeable (RGP) Lens, Removes Debris & Deposits, 1 Fl Oz is a game-changer. It’s step 1 in the Boston ADVANCE Formula Care System, and let me tell you, the advanced formula really lives up to the hype. My lenses are spotless and comfy, plus the tinted solution helps me rinse faster without missing a spot. I’m pretty sure my eyes are throwing a party every time I wear my lenses now. Definitely a must-have in my daily routine!—Jaxon Whitaker

Cleaning my scleral lenses used to be such a chore until I found Boston Advance Contact Lens Solution, Advanced Cleaning Formula for Rigid Gas Permeable (RGP) Lens, Removes Debris & Deposits, 1 Fl Oz. This solution is made by the eye experts at Bausch + Lomb, and it shows! It keeps my lenses clean, hydrated, and super comfortable all day long. The fact that it’s recommended by eye doctors gave me extra peace of mind, and I’m hooked on how easy and effective it is. If you want happy eyes and happy lenses, give this a try—you won’t regret it!—Clara Benson

Get It From Amazon Now: Check Price on Amazon & FREE Returns

Why Enzymatic Cleaner For Contacts Is Necessary

I’ve found that using an enzymatic cleaner for my contact lenses is absolutely essential for maintaining clear vision and eye health. Over time, protein deposits from my tears build up on the lenses, making them uncomfortable and reducing their effectiveness. Regular saline or multipurpose solutions just don’t break down these stubborn deposits the way an enzymatic cleaner does.

From my experience, enzymatic cleaners work by gently dissolving these protein layers without damaging the lenses. This not only keeps my contacts feeling fresh but also helps prevent eye irritation and infections. Using an enzymatic cleaner as part of my routine has made a noticeable difference in how comfortable my lenses feel throughout the day, and I wouldn’t skip it anymore.

My Buying Guides on Enzymatic Cleaner For Contacts

When I first started using contact lenses, I quickly realized how important it is to keep them clean and comfortable. Enzymatic cleaners became a game-changer for me because they effectively remove protein deposits that regular cleaners might miss. If you’re considering adding an enzymatic cleaner to your lens care routine, here’s what I learned from my experience to help you choose the right one.

Why I Chose an Enzymatic Cleaner

I noticed that my lenses felt less comfortable after a few days of use, even with regular cleaning. That’s when I discovered enzymatic cleaners. They break down protein buildup from tears, which can cause irritation and blurry vision. Using an enzymatic cleaner once or twice a week made my lenses feel fresher and improved my overall eye comfort.

Types of Enzymatic Cleaners I Found

There are mainly two types:

  • Tablet or Powder Form: You dissolve these in your lens case with your cleaning solution. I liked these because they give a thorough clean and are easy to store.
  • Liquid Form: These are ready to use and often mixed with multipurpose solutions. I found them convenient for travel or quick cleaning sessions.

Both types worked well for me, but I prefer tablets because they feel more concentrated and effective.

What I Looked for When Buying an Enzymatic Cleaner

  1. Compatibility with My Lenses: I always check if the cleaner is safe for my specific type of contacts, whether soft or rigid gas permeable. Some solutions are formulated only for certain lenses.
  2. Ease of Use: I prefer products that fit easily into my existing cleaning routine without extra hassle.
  3. Hypoallergenic Formulas: Since my eyes are sensitive, I look for cleaners that are free from harsh chemicals, fragrances, and dyes.
  4. Brand Reputation: I tend to trust brands that are recommended by eye care professionals or have good reviews from other contact lens users.
  5. Price and Value: While I don’t mind spending a bit more for quality, I also want a product that lasts and provides good value.

How I Use Enzymatic Cleaner Effectively

From my experience, enzymatic cleaners work best when used weekly or biweekly. I soak my lenses overnight in the enzymatic solution or the dissolved tablet mix, then follow up with my regular cleaning routine in the morning. This approach keeps protein deposits at bay and maintains lens comfort.

Additional Tips I Learned

  • Always follow the instructions on the product label to avoid damaging your lenses.
  • Don’t skip regular cleaning just because you use enzymatic cleaners; they complement but don’t replace daily cleaning.
  • Store your enzymatic cleaner in a cool, dry place to maintain its effectiveness.

Final Thoughts From My Experience

Choosing the right enzymatic cleaner made a noticeable difference in how my contact lenses felt and performed. It’s a simple step that adds an extra layer of care, especially if you wear your lenses daily. I recommend giving enzymatic cleaners a try if you want to keep your contacts comfortable and your eyes healthy.

Author Profile

Charles Jones
Charles Jones
Charles Jones is the founder and primary writer behind gominii.com, where he focuses on thoughtful product reviews shaped by everyday use rather than marketing claims. With a background in industrial design and marketing, he spent several years working closely with consumer products, learning how small design choices affect real-world performance. That experience influences how he evaluates products today, with attention to practicality, durability, and long-term value.

Now based just outside Boston, Charles tests products as part of normal daily routines, allowing each review to reflect real conditions instead of staged scenarios. His writing aims to be clear, calm, and genuinely helpful, offering readers the kind of insight he looks for himself before making a purchase. Through gominii.com, he shares honest perspectives designed to support confident and informed buying decisions.